Severe Rhabdomyolysis in Glucose-6-Phosphate Dehydrogenase Deficiency

Authors

Balraj Singh
Parminder Kaur
Kok Hoe ChanFollow
Robert G. Lahita MD, New York Medical College
Michael MaroulesFollow
Chandra Chandran, New York Medical College

DOI

10.1016/j.amjms.2020.03.018

Journal Title

The American Journal of the Medical Sciences

First Page

72

Last Page

74

Document Type

Review Article

Publication Date

7-2020

Department

Medicine

Abstract

Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency is an X-linked genetic disorder associated with intravascular hemolysis. Rhabdomyolysis with myoglobinuria in a patient with G6PD deficiency is a very rare manifestation, in fact, to the best of our knowledge, only a few case reports have been published in the literature to date. Herein, we report an unusual presentation of a 33-year-old male with G6PD deficiency with multiple episodes of severe rhabdomyolysis with no significant concurrent hemolysis. This case supports the hypothesis that rhabdomyolysis may be a rare manifestation of G6PD deficiency, though the exact causation still remains unclear.

Recommended Citation

Singh, B., Kaur, P., Chan, K., Lahita, R. G., Maroules, M., & Chandran, C. (2020). Severe Rhabdomyolysis in Glucose-6-Phosphate Dehydrogenase Deficiency. The American Journal of the Medical Sciences, 360 (1), 72-74. https://doi.org/10.1016/j.amjms.2020.03.018