Peripartum Cardiomyopathy Incidence, Risk Factors, Diagnostic Criteria, Pathophysiology, and Treatment Options

Authors

Nicole K. Zagelbaum
Jasjit Bhinder
Chhaya Aggarwal Gupta, New York Medical CollegeFollow
William H. Frishman, New York Medical CollegeFollow
Wilbert S. Aronow, New York Medical CollegeFollow

DOI

10.1097/CRD.0000000000000249

Journal Title

Cardiology in Review

First Page

148

Last Page

155

Document Type

Review Article

Publication Date

5-2020

Department

Medicine

Abstract

Peripartum cardiomyopathy is a rare and a severe form of heart failure that affects women during pregnancy or shortly after delivery. Risk factors include advanced age, race, multiparity, multifetal pregnancy, socioeconomic disparity, and medical comorbidities including systemic hypertension, diabetes, asthma, and anemia. Peripartum cardiomyopathy is associated with increased morbidity and mortality, as well as a detrimental long-term impact on quality of life. Its etiology is not clear, although it is thought to be a combined effect of a hyperdynamic fluid state associated with pregnancy, hormonal changes unique to gestation, and a genetic predisposition. There is no current expert consensus on an optimal treatment regimen. This article will provide a comprehensive review and update on this important disease state.

Recommended Citation

Zagelbaum, N. K., Bhinder, J., Gupta, C. A., Frishman, W. H., & Aronow, W. S. (2020). Peripartum Cardiomyopathy Incidence, Risk Factors, Diagnostic Criteria, Pathophysiology, and Treatment Options. Cardiology in Review, 28 (3), 148-155. https://doi.org/10.1097/CRD.0000000000000249