NYMC Faculty Publications

Management of Small Unruptured Intracranial Aneurysms: To Treat or Not to Treat?

Author Type(s)

Faculty

Journal Title

Cardiology in Review

First Page

33

Last Page

38

Document Type

Article

Publication Date

1-2021

Department

Neurosurgery

Second Department

Neurology

Abstract

Unruptured intracranial aneurysms measuringliterature, the 3 main treatments for an unruptured intracranial aneurysm are conservative management with follow-up imaging, endovascular coiling, or surgical clipping. However, there remains no consensus on the best treatment approach. The natural history of the aneurysm and risk factors for aneurysm rupture must be considered to individualize treatment. Models including population, hypertension, age, size of aneurysm, earlier subarachnoid hemorrhage from a prior aneurysm, site of aneurysm score, Unruptured Intracranial Aneurysm Treatment Score, and advanced neuroimaging can assist physicians in assessing the risk of aneurysm rupture. Macrophages and other inflammatory modulators have been elucidated as playing a role in intracranial aneurysm progression and eventual rupture. Further studies need to be conducted to explore the effects of therapeutic drugs targeting inflammatory modulators.

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