NYMC Faculty Publications
Management of Small Unruptured Intracranial Aneurysms: To Treat or Not to Treat?
Author Type(s)
Faculty
DOI
10.1097/CRD.0000000000000333
Journal Title
Cardiology in Review
First Page
33
Last Page
38
Document Type
Article
Publication Date
1-2021
Department
Neurosurgery
Second Department
Neurology
Abstract
Unruptured intracranial aneurysms measuringliterature, the 3 main treatments for an unruptured intracranial aneurysm are conservative management with follow-up imaging, endovascular coiling, or surgical clipping. However, there remains no consensus on the best treatment approach. The natural history of the aneurysm and risk factors for aneurysm rupture must be considered to individualize treatment. Models including population, hypertension, age, size of aneurysm, earlier subarachnoid hemorrhage from a prior aneurysm, site of aneurysm score, Unruptured Intracranial Aneurysm Treatment Score, and advanced neuroimaging can assist physicians in assessing the risk of aneurysm rupture. Macrophages and other inflammatory modulators have been elucidated as playing a role in intracranial aneurysm progression and eventual rupture. Further studies need to be conducted to explore the effects of therapeutic drugs targeting inflammatory modulators.
Recommended Citation
Elkun, Y., Cooper, J., Kamal, H., Dakay, K., Nuoaman, H., Adnan, Y., Dodson, V., Nuoman, R., Kaur, K., Kurian, C., Sahni, R., Gandhi, C., & Al-Mufti, F. (2021). Management of Small Unruptured Intracranial Aneurysms: To Treat or Not to Treat?. Cardiology in Review, 29 (1), 33-38. https://doi.org/10.1097/CRD.0000000000000333