NYMC Faculty Publications
Hygromycin A in the Lymelight
Author Type(s)
Faculty
DOI
10.1016/j.chom.2021.10.007
Journal Title
Cell Host & Microbe
First Page
1599
Last Page
1601
Document Type
Response or Comment
Publication Date
11-10-2021
Department
Pathology, Microbiology and Immunology
Keywords
Borrelia burgdorferi, Borrelia burgdorferi Group, Cinnamates, Humans, Hygromycin B, Lyme Disease
Disciplines
Medicine and Health Sciences
Abstract
Lyme disease, which is caused by the spirochete Borrelia burgdorferi, is on the rise. Current treatment relies on broad-spectrum antibiotics that perturb the gut microbiome. In a recent paper in Cell, Leimer et al. demonstrate the utility of a long-forgotten antibiotic, Hygromycin A, as a spirochete-specific antibacterial that is conducive to gut health.
Recommended Citation
Arnaboldi, P. M., & Narasimhan, S. (2021). Hygromycin A in the Lymelight. Cell Host & Microbe, 29 (11), 1599-1601. https://doi.org/10.1016/j.chom.2021.10.007