Hygromycin A in the Lymelight

Authors

Paul Michael Arnaboldi, New York Medical CollegeFollow
Sukanya Narasimhan

Author Type(s)

Faculty

Journal Title

Cell Host & Microbe

First Page

1599

Last Page

1601

Document Type

Response or Comment

Publication Date

11-10-2021

Department

Pathology, Microbiology and Immunology

Abstract

Lyme disease, which is caused by the spirochete Borrelia burgdorferi, is on the rise. Current treatment relies on broad-spectrum antibiotics that perturb the gut microbiome. In a recent paper in Cell, Leimer et al. demonstrate the utility of a long-forgotten antibiotic, Hygromycin A, as a spirochete-specific antibacterial that is conducive to gut health.

Recommended Citation

Arnaboldi, P. M., & Narasimhan, S. (2021). Hygromycin A in the Lymelight. Cell Host & Microbe, 29 (11), 1599-1601. https://doi.org/10.1016/j.chom.2021.10.007