NYMC Faculty Publications
Obstructive Sleep Apnoea and Cardiovascular Disease: A Literature Review
Author Type(s)
Faculty
DOI
10.5114/aoms.2019.88558
Journal Title
Archives of Medical Science
First Page
1200
Last Page
1212
Document Type
Article
Publication Date
10-8-2021
Department
Medicine
Abstract
As obesity becomes more common worldwide, the prevalence of obstructive sleep apnoea (OSA) continues to rise. Obstructive sleep apnoea is a well-known disorder that causes chronic intermittent hypoxia (CIH), which is considered a risk factor for atherosclerosis directly and indirectly. Ischaemic heart disease remains the leading cause of death. Most risk factors for atherosclerosis are well understood. However, other factors such as CIH are less well understood. Several studies have investigated the pathophysiology of CIH, attempting to uncover its link to atherosclerosis and to determine whether OSA treatment can be a therapeutic modality to modify the risk for atherosclerosis. In this article, we will review the pathophysiology of OSA as an independent risk factor for cardiovascular disease and discuss the most common markers that have been studied. We will also examine the potential impact of OSA management as a risk factor modifier on the reversibility of atherosclerosis.
Recommended Citation
Assallum, H., Song, T., Aronow, W. S., & Chandy, D. (2021). Obstructive Sleep Apnoea and Cardiovascular Disease: A Literature Review. Archives of Medical Science, 17 (5), 1200-1212. https://doi.org/10.5114/aoms.2019.88558