Gitelman Syndrome Provisionally Diagnosed During the First Presentation of Diabetic Ketoacidosis

Authors

Mojgan Jalalzadeh
David Garcia Goncalves de Brito
Shobhana Chaudhari, New York Medical CollegeFollow
Armeen D. Poor, New York Medical College
Donald Baumstein, New York Medical CollegeFollow

Author Type(s)

Faculty

Journal Title

Cureus

First Page

14253

Last Page

14253

Document Type

Case Report

Publication Date

4-2-2021

Department

Medicine

Abstract

Gitelman syndrome (GS) is an autosomal recessive disease characterized by hypokalemia, hypomagnesemia, metabolic alkalosis, and hypocalciuria. It is caused by mutations in gene SLC12A3 (located in chromosome 16q) encoding NaCl cotransporter. GS is usually asymptomatic for several years and is diagnosed in late childhood or adulthood. The association between GS and diabetic ketoacidosis (DKA) is rare. We present a case of a 25-year-old man with newly diagnosed diabetes mellitus and DKA with profound hypokalemia and hypomagnesemia who was provisionally found to have GS.

Recommended Citation

Jalalzadeh, M., Garcia Goncalves de Brito, D., Chaudhari, S., Poor, A. D., & Baumstein, D. (2021). Gitelman Syndrome Provisionally Diagnosed During the First Presentation of Diabetic Ketoacidosis. Cureus, 13 (4), 14253-14253. https://doi.org/10.7759/cureus.14253