Obesity and Outcomes Following Cardiogenic Shock Requiring Acute Mechanical Circulatory Support
BACKGROUND: The association of obesity on outcomes in patients with cardiogenic shock requiring acute mechanical circulatory support has not been thoroughly investigated.
METHODS: We evaluated the National Readmission Database for adults with either acute myocardial infarction or heart failure complicated by cardiogenic shock requiring acute mechanical circulatory support between January 2016 and November 2017. Exposure was assessed using
RESULTS: The survey-weighted sample included a total of 35 555 hospitalizations with a mean age of 65.4±0.2 years and 29.8% females. Obesity was associated with higher in-hospital mortality (no obesity, 26.4% [BMI, 20.0-29.9] versus class I obesity, 25.0% [BMI, 30.0-34.9] versus class II obesity, 28.7% [BMI, 35.0-39.9] versus class III obesity, 34.9% [BMI, ≥40];
CONCLUSIONS: Among adults with acute myocardial infarction or acute heart failure resulting in cardiogenic shock requiring acute mechanical circulatory support, younger adults with class II and class III obesity and older patients with class III obesity have a higher risk of in-hospital mortality compared with nonobese patients.
Sreenivasan, J., Khan, M., Sharedalal, P., Hooda, U., Fudim, M., Demmer, R. T., Yuzefpolskaya, M., Ahmad, H., Khan, S. S., Lanier, G. M., Colombo, P. C., & Rich, J. D. (2021). Obesity and Outcomes Following Cardiogenic Shock Requiring Acute Mechanical Circulatory Support. Circulation. Heart Failure, 14 (3), 007937-007937. https://doi.org/10.1161/CIRCHEARTFAILURE.120.007937