NYMC Faculty Publications
Antineutrophil Cytoplasmic Antibody-Associated Glomerulonephritis in a Case of Scleroderma After Recent Diagnosis With COVID-19
Author Type(s)
Faculty
DOI
10.7759/cureus.12485
Journal Title
Cureus
First Page
12485
Last Page
12485
Document Type
Case Report
Publication Date
1-4-2021
Department
Medicine
Abstract
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a rare occurrence in systemic sclerosis (SSc) patients. AAV is an inflammatory disease that can lead to kidney failure due to the infiltration of mononuclear cells and the destruction of blood vessels. Also, crescentic glomerulonephritis (GN) has rarely been reported with coronavirus disease 2019 (COVID-19) and acute tubular injury is the most common renal pathology lesion in these patients. We present a rare case of a 46-year-old woman with SSc with new onset of renal failure after a recent diagnosis of COVID-19. Her serology was positive for p-ANCA and myeloperoxidase antibodies. Kidney biopsy was done and showed crescentic GN. We suggest during this pandemic, patients with an immunological disorder that are infected with COVID-19 be closely monitored for any organ involvement.
Recommended Citation
Jalalzadeh, M., Valencia-Manrique, J. C., Boma, N., Chaudhari, A., & Chaudhari, S. (2021). Antineutrophil Cytoplasmic Antibody-Associated Glomerulonephritis in a Case of Scleroderma After Recent Diagnosis With COVID-19. Cureus, 13 (1), 12485-12485. https://doi.org/10.7759/cureus.12485
