NYMC Faculty Publications
Epidemiology, Diagnosis, Staging and Multimodal Therapy of Esophageal and Gastric Tumors
Author Type(s)
Faculty
DOI
10.3390/cancers13030582
Journal Title
Cancers (Basel)
First Page
582
Document Type
Review Article
Publication Date
2-2-2021
Department
Medicine
Abstract
Gastric and esophageal tumors are diverse neoplasms that involve mucosal and submucosal tissue layers and include squamous cell carcinomas, adenocarcinomas, spindle cell neoplasms, neuroendocrine tumors, marginal B cell lymphomas, along with less common tumors. The worldwide burden of esophageal and gastric malignancies is significant, with esophageal and gastric cancer representing the ninth and fifth most common cancers, respectively. The approach to diagnosis and staging of these lesions is multimodal and includes a combination of gastrointestinal endoscopy, endoscopic ultrasound, and cross-sectional imaging. Likewise, therapy is multidisciplinary and combines therapeutic endoscopy, surgery, radiotherapy, and systemic chemotherapeutic tools. Future directions for diagnosis of esophageal and gastric malignancies are evolving rapidly and will involve advances in endoscopic and endosonographic techniques including tethered capsules, optical coherence tomography, along with targeted cytologic and serological analyses.
Recommended Citation
Cummings, D., Wong, J., Palm, R., Hoffe, S., Almhanna, K., & Vignesh, S. (2021). Epidemiology, Diagnosis, Staging and Multimodal Therapy of Esophageal and Gastric Tumors. Cancers (Basel), 13 (3), 582. https://doi.org/10.3390/cancers13030582
