Sex Differences in Heart Failure Hospitalisation Risk Following Acute Myocardial Infarction

Authors

Srikanth Yandrapalli
Aaqib Malik, New York Medical CollegeFollow
Gayatri Pemmasani
Wilbert S. Aronow, New York Medical CollegeFollow
Falak Shah, New York Medical College
Gregg Lanier, New York Medical CollegeFollow
Howard Cooper, New York Medical College
Diwakar Jain, New York Medical CollegeFollow
Srihari Naidu, New York Medical CollegeFollow
William Frishman, New York Medical CollegeFollow
Julio Panza, New York Medical CollegeFollow

Author Type(s)

Faculty

Journal Title

Heart

First Page

1657

Last Page

1663

Document Type

Article

Publication Date

10-2021

Department

Medicine

Abstract

OBJECTIVE: We evaluated the sex differences in 6-month heart failure (HF) hospitalisation risk in acute myocardial infarction (AMI) survivors.

METHODS: For this retrospective cohort analysis, adult survivors of an AMI between January and June 2014 were identified from the US Nationwide Readmissions Database. The primary outcome was a HF hospitalisation within 6 months. Secondary outcomes were fatal HF hospitalisation and the composite of index in-hospital HF or 6-month HF hospitalisation.

RESULTS: Of 237 549 AMI survivors, females (37.9%) were older (70±14 years vs 65±13 years; p

CONCLUSION: In a large all-comers AMI survivors' cohort, females had a higher HF hospitalisation risk that persisted after adjustment for baseline risk differences. This was consistent across several clinically relevant subgroups and was evident early on after the AMI.

Recommended Citation

Yandrapalli, S., Malik, A., Pemmasani, G., Aronow, W. S., Shah, F., Lanier, G., Cooper, H., Jain, D., Naidu, S., Frishman, W., & Panza, J. (2021). Sex Differences in Heart Failure Hospitalisation Risk Following Acute Myocardial Infarction. Heart, 107 (20), 1657-1663. https://doi.org/10.1136/heartjnl-2020-318306