Sex Differences in Heart Failure Hospitalisation Risk Following Acute Myocardial Infarction
OBJECTIVE: We evaluated the sex differences in 6-month heart failure (HF) hospitalisation risk in acute myocardial infarction (AMI) survivors.
METHODS: For this retrospective cohort analysis, adult survivors of an AMI between January and June 2014 were identified from the US Nationwide Readmissions Database. The primary outcome was a HF hospitalisation within 6 months. Secondary outcomes were fatal HF hospitalisation and the composite of index in-hospital HF or 6-month HF hospitalisation.
RESULTS: Of 237 549 AMI survivors, females (37.9%) were older (70±14 years vs 65±13 years; p
CONCLUSION: In a large all-comers AMI survivors' cohort, females had a higher HF hospitalisation risk that persisted after adjustment for baseline risk differences. This was consistent across several clinically relevant subgroups and was evident early on after the AMI.
Yandrapalli, S., Malik, A., Pemmasani, G., Aronow, W. S., Shah, F., Lanier, G., Cooper, H., Jain, D., Naidu, S., Frishman, W., & Panza, J. (2021). Sex Differences in Heart Failure Hospitalisation Risk Following Acute Myocardial Infarction. Heart, 107 (20), 1657-1663. https://doi.org/10.1136/heartjnl-2020-318306