NYMC Faculty Publications

Sex Differences in Heart Failure Hospitalisation Risk Following Acute Myocardial Infarction

Author Type(s)

Faculty

DOI

10.1136/heartjnl-2020-318306

Journal Title

Heart

First Page

1657

Last Page

1663

Document Type

Article

Publication Date

10-2021

Department

Medicine

Keywords

Adolescent, Adult, Aged, Female, Follow-Up Studies, Heart Failure, Hospitalization, Humans, Incidence, Inpatients, Male, Middle Aged, Myocardial Infarction, Prognosis, Retrospective Studies, Risk Assessment, Risk Factors, Sex Distribution, Sex Factors, United States, Young Adult

Disciplines

Medicine and Health Sciences

Abstract

OBJECTIVE: We evaluated the sex differences in 6-month heart failure (HF) hospitalisation risk in acute myocardial infarction (AMI) survivors.

METHODS: For this retrospective cohort analysis, adult survivors of an AMI between January and June 2014 were identified from the US Nationwide Readmissions Database. The primary outcome was a HF hospitalisation within 6 months. Secondary outcomes were fatal HF hospitalisation and the composite of index in-hospital HF or 6-month HF hospitalisation.

RESULTS: Of 237 549 AMI survivors, females (37.9%) were older (70±14 years vs 65±13 years; p

CONCLUSION: In a large all-comers AMI survivors' cohort, females had a higher HF hospitalisation risk that persisted after adjustment for baseline risk differences. This was consistent across several clinically relevant subgroups and was evident early on after the AMI.

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