NYMC Faculty Publications

Small Lymphocytic Lymphoma of the Prostate Mimicking a PIRADS 5 Lesion that Resolved after Systemic Treatment

Author Type(s)

Faculty

DOI

10.1016/j.eucr.2021.101775

Journal Title

Urology Case Reports

First Page

101775

Last Page

101775

Document Type

Case Report

Publication Date

7-2021

Department

Urology

Second Department

Radiology

Third Department

Pathology, Microbiology and Immunology

Abstract

Prostatic PIRADS 4 and 5 lesions on multiparametric MRI typically represent adenocarcinoma with small lymphocytic lymphoma being a rare pathological finding. We report a case of small lymphocytic lymphoma masquerading as PIRADS 4 and 5 lesions with associated lymphadenopathy in a 69-year-old male on active surveillance for low-risk prostate cancer that was subsequently confirmed on targeted and systematic prostate biopsy. Following treatment of lymphoma with ibrutinib, there was complete resolution of the PIRADS lesions on follow-up mpMRI.

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