Small Lymphocytic Lymphoma of the Prostate Mimicking a PIRADS 5 Lesion that Resolved after Systemic Treatment

Authors

Tiffany H Wong
David Ambinder
Milana Flusberg, New York Medical College
Fouzia Shakil, New York Medical CollegeFollow
John L. Phillips, New York Medical CollegeFollow
Nathan C. Wong, New York Medical College

Author Type(s)

Faculty

Journal Title

Urology Case Reports

First Page

101775

Last Page

101775

Document Type

Case Report

Publication Date

7-2021

Department

Urology

Second Department

Radiology

Third Department

Pathology, Microbiology and Immunology

Abstract

Prostatic PIRADS 4 and 5 lesions on multiparametric MRI typically represent adenocarcinoma with small lymphocytic lymphoma being a rare pathological finding. We report a case of small lymphocytic lymphoma masquerading as PIRADS 4 and 5 lesions with associated lymphadenopathy in a 69-year-old male on active surveillance for low-risk prostate cancer that was subsequently confirmed on targeted and systematic prostate biopsy. Following treatment of lymphoma with ibrutinib, there was complete resolution of the PIRADS lesions on follow-up mpMRI.

Recommended Citation

Wong, T., Ambinder, D., Flusberg, M., Shakil, F., Phillips, J. L., & Wong, N. C. (2021). Small Lymphocytic Lymphoma of the Prostate Mimicking a PIRADS 5 Lesion that Resolved after Systemic Treatment. Urology Case Reports, 39, 101775-101775. https://doi.org/10.1016/j.eucr.2021.101775