NYMC Faculty Publications
Is Compensation Prediction Score Valid for Contralateral Kidney After Living-Donor Nephrectomy in the United States?
Author Type(s)
Faculty, Resident/Fellow
Journal Title
Transplantation Proceedings
First Page
237
Last Page
241
Document Type
Article
Publication Date
3-1-2022
Department
Surgery
Second Department
Medicine
Abstract
BACKGROUND: Compensation after living donor nephrectomy is well known, and a compensation prediction score (CPS) was made in Japan previously. The aim of this study was to perform external validation of CPS in the United States. METHODS: We studied retrospectively 78 living donor nephrectomies in our institution. We defined a favorable compensation as a postdonation estimated glomerular filtration rate (eGFR) at 1 year of >60% of the predonation eGFR. We analyzed the living donors' clinical characteristics and outcomes and validated CPS score. RESULTS: The median (range) donor age was 43 (21-63) years, and median body mass index was 26.9 (18.3-35.9) kg/m. Forty-four percent of donors were White. The donor predonation eGFR was 105 (61-134) mL/min/1.73 m, and the postdonation eGFR at 1 year was 73.2 (0-115) mL/min/1.73 m. Eighty-three percent of donors had a favorable compensation. The CPS was 9.6 (1.6-15.6) and showed strong diagnostic accuracy for predicting favorable compensation (area under the curve, 0.788; 95% confidence interval, 0.652-0.924; P = .001). The CPS showed a significant positive correlation with the postdonation eGFR at 1 year (R = 0.54; P < .001). CONCLUSIONS: In the United States, the CPS would be a valid tool with which to predict a favorable compensation of remnant kidney function.
Recommended Citation
Okumura, K., Grace, H., Sogawa, H., Veillette, G., John, D., Singh, N., Glicklich, D., Nishida, S., & Diflo, T. (2022). Is Compensation Prediction Score Valid for Contralateral Kidney After Living-Donor Nephrectomy in the United States?. Transplantation Proceedings, 54 (2), 237-241. https://doi.org/10.1016/j.transproceed.2021.08.067
