The Role of Zinc in Cardiovascular Disease

Authors

Farhana Begum, From the Departments of Medicine, Zucker School of Medicine-Northwell NS/LIJ, Manhasset, NY.
Hay Me Me, New York Medical College/Westchester Medical Center, Valhalla, NY.
Marta Christov, New York Medical College/Westchester Medical Center, Valhalla, NY.Follow

Author Type(s)

Faculty

DOI

10.1097/CRD.0000000000000382

Journal Title

Cardiology in Review

First Page

100

Last Page

108

Document Type

Article

Publication Date

3-1-2022

Department

Medicine

Abstract

Zinc is an essential trace element due to its role as a key part of human enzymatic activity. As a cofactor in metalloenzymes and metalloproteins, zinc participates in diverse biological functions, including gene transcription, translation, and replication, phagocytosis, and immunoglobulin and cytokine production. In this review, we will focus on the role of zinc in the cardiovascular system, including heart failure, vascular calcification, and myocardial infarction. We will further highlight the role of zinc in cardiovascular pathology in individuals with chronic kidney disease, and type II diabetes mellitus, groups uniquely at risk for cardiovascular morbidity and mortality.

Recommended Citation

Begum, F., Me, H. M., & Christov, M. (2022). The Role of Zinc in Cardiovascular Disease. Cardiology in Review, 30 (2), 100-108. https://doi.org/10.1097/CRD.0000000000000382