Infective Endocarditis After Transcatheter Aortic Valve Implantation: A Systematic Review

Authors

Ahmed Hassanin, From the Department of Cardiology, Westchester Medical Center and New York Medical College, Valhalla, NY.
Hesham Afify, Department of Internal Medicine, University of Central Florida College of Medicine, Orlando, FL.
Salma Zook, Houston Methodist DeBakey Heart & Vascular Center, Houston, TX.
William H. Frishman, From the Department of Cardiology, Westchester Medical Center and New York Medical College, Valhalla, NY.Follow
Wilbert S. Aronow, From the Department of Cardiology, Westchester Medical Center and New York Medical College, Valhalla, NY.Follow

Author Type(s)

Faculty

DOI

10.1097/CRD.0000000000000460

Journal Title

Cardiology in Review

First Page

93

Last Page

98

Document Type

Article

Publication Date

3-1-2023

Department

Medicine

Abstract

Infective endocarditis (IE) after transcatheter aortic valve implantation (TAVI) is a rare but potentially fatal event. In this systematic review, we searched PubMed and Embase for large TAVI studies and registries to identify the incidence, presentation, microbiology, risk factors, and outcomes of IE in this population. After application of the selection criteria and quality assessment, 8 studies representing 255,310 TAVR cases and 4218 cases of IE qualified for this review. IE following TAVI is uncommon with an incidence of 0.87 to 1.7 events per 100 person-years. Most events occur in the first year following valve implantation. Staphylococcus , Enterococcus , and Streptococcus species are the most common pathogens. Risk factors include age, sex, concomitant comorbidities, and procedural factors. Outcomes are dismal, and surgical intervention is rare in this population.

Recommended Citation

Hassanin, A., Afify, H., Zook, S., Frishman, W. H., & Aronow, W. S. (2023). Infective Endocarditis After Transcatheter Aortic Valve Implantation: A Systematic Review. Cardiology in Review, 31 (2), 93-98. https://doi.org/10.1097/CRD.0000000000000460