NYMC Faculty Publications
Dual Antiplatelet Therapy With Concomitant Anticoagulation: Current Perspectives on Triple Therapy
Author Type(s)
Resident/Fellow, Faculty
DOI
10.5114/amsad/161172
Journal Title
Archives of Medical Sciences. Atherosclerotic Diseases
First Page
e13
Last Page
e18
Document Type
Article
Publication Date
1-1-2023
Department
Medicine
Abstract
Anticoagulation and antiplatelet therapy are individually mainstays of treatment for multiple cardiovascular conditions. Antiplatelet therapy, most commonly with dual agents, is vital in the setting of coronary artery disease with acute coronary syndrome requiring percutaneous coronary intervention to prevent in-stent complications. A multitude of cardiovascular conditions with increased thromboembolic risk also require anticoagulation, including atrial fibrillation, venous or arterial thrombosis, and prosthetic heart valves to name a few. There is often an overlap in comorbidities as our patient population ages and becomes more complex, frequently necessitating a combination of both anticoagulation and antiplatelet agents, known as "triple therapy". To reduce or treat thromboembolic disease states as well as reduce platelet aggregation for coronary stent protection, many patients are placed at an increased bleeding risk without compelling evidence of reduction in major adverse cardiac events. With this comprehensive review of the existing literature, we aim to analyse different strategies and durations of triple therapy medication regimens.
Recommended Citation
Patail, H., Sharma, T., Bali, A. D., Isath, A., Aronow, W. S., & Haidry, S. A. (2023). Dual Antiplatelet Therapy With Concomitant Anticoagulation: Current Perspectives on Triple Therapy. Archives of Medical Sciences. Atherosclerotic Diseases, 8, e13-e18. https://doi.org/10.5114/amsad/161172