NYMC Faculty Publications
Patients With Infective Endocarditis and Increased Cardiac Troponin I Levels Have a Higher Incidence of In-Hospital Mortality and Valve Replacement Than Those With Normal Cardiac Troponin I Levels
Author Type(s)
Faculty
Journal Title
Cardiology
First Page
202
Last Page
204
Document Type
Article
Publication Date
1-1-2009
Department
Medicine
Keywords
Aged, Biomarkers, Endocarditis, Bacterial, Female, Heart Valve Diseases, Heart Valve Prosthesis Implantation, Hospital Mortality, Humans, Incidence, Male, Middle Aged, Predictive Value of Tests, Prognosis, Risk Factors, Troponin I
Disciplines
Medicine and Health Sciences
Abstract
OBJECTIVES: To investigate the association of increased cardiac troponin I levels with in-hospital mortality and valve replacement in patients with infective endocarditis (IE).
METHODS: The 62 patients included 36 men and 26 women, with a mean age of 60 +/- 9 years, with IE diagnosed by the Duke criteria. All 62 patients had blood drawn for measurement of cardiac troponin I levels. A cardiac troponin I level >0.4 ng/ml was considered increased. All 62 patients underwent transesophageal echocardiography. Student's t tests were used to analyze continuous variables. chi(2) tests were used to analyze dichotomous variables.
RESULTS: Transesophageal echocardiography diagnosed valvular vegetations in 56 of the 62 patients (90%). Cardiac troponin I levels were increased in 35 of the 62 patients (57%). In-hospital mortality or valve replacement occurred in 18 of 35 patients (51%) with increased cardiac troponin I levels versus 4 of 27 patients (15%) with normal cardiac troponin I levels (p < 0.005).
CONCLUSIONS: Patients with IE and increased cardiac troponin I levels have a higher incidence of in-hospital mortality or valve replacement than those with normal cardiac troponin I levels.
Recommended Citation
Tsenovoy, P., Aronow, W., Joseph, J., & Kopacz, M. (2009). Patients With Infective Endocarditis and Increased Cardiac Troponin I Levels Have a Higher Incidence of In-Hospital Mortality and Valve Replacement Than Those With Normal Cardiac Troponin I Levels. Cardiology, 112 (3), 202-204. Retrieved from https://touroscholar.touro.edu/nymc_fac_pubs/4699
