NYMC Faculty Publications

Predictors of Gastrointestinal Bleeding in Patients Following Left Ventricular Assist Device Implantation: a Systematic Review and Meta-Analysis

Author Type(s)

Faculty

DOI

10.2217/fca-2022-0054

Journal Title

Future Cardiology

First Page

957

Last Page

967

Document Type

Review Article

Publication Date

12-2022

Department

Medicine

Keywords

Humans, Heart-Assist Devices, Heart Failure, Gastrointestinal Hemorrhage, Risk Factors, Retrospective Studies

Disciplines

Medicine and Health Sciences

Abstract

Aim: Our study aims to provide a more holistic understanding of the available data and predictive risk factors for gastrointestinal bleed (GIB). Materials & methods: We searched MEDLINE, Embase, Cochrane Central Register of Controlled Trials and Web of Science Core Collection and calculated relative risk and meta-regression was utilized to evaluate for risk factors in order to assess the effect of covariates. Results: Our meta-analysis reported a pooled prevalence rate of GIB of 24.4%. Meta-regression analysis did not yield a statistically significant association between GIB and risk factors, including age, gender, hypertension, chronic kidney disease and diabetes. Conclusion: Studies investigating larger sample sizes are required for conclusive findings.

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