Cross-Reactive Epitopes in Borrelia Burgdorferi P66

Authors

Paul M. Arnaboldi, Biopeptides Corp., East Setauket, New York, USA, and Department of Microbiology and Immunology, New York Medical College, Valhalla, New York, USA paul_arnaboldi@nymc.edu.Follow
Raymond J. Dattwyler, Biopeptides Corp., East Setauket, New York, USA, and Department of Microbiology and Immunology, New York Medical College, Valhalla, New York, USA.

Author Type(s)

Faculty

DOI

10.1128/CVI.00217-15

Journal Title

Clinical and Vaccine Immunology

First Page

840

Last Page

3

Document Type

Article

Publication Date

7-1-2015

Abstract

Epitope mapping of the p66 outer membrane protein of Borrelia burgdorferi revealed that the protein contains numerous cross-reactive linear epitopes recognized by serum antibody in the majority of individuals tested, regardless of Lyme disease history, limiting the usefulness of this antigen in Lyme disease serodiagnostic assays.

Recommended Citation

Arnaboldi, P. M., & Dattwyler, R. J. (2015). Cross-Reactive Epitopes in Borrelia Burgdorferi P66. Clinical and Vaccine Immunology, 22 (7), 840-3. https://doi.org/10.1128/CVI.00217-15