NYMC Faculty Publications

Cross-Reactive Epitopes in Borrelia Burgdorferi P66

Author Type(s)

Faculty

DOI

10.1128/CVI.00217-15

Journal Title

Clinical and Vaccine Immunology

First Page

840

Last Page

3

Document Type

Article

Publication Date

7-1-2015

Disciplines

Medicine and Health Sciences

Abstract

Epitope mapping of the p66 outer membrane protein of Borrelia burgdorferi revealed that the protein contains numerous cross-reactive linear epitopes recognized by serum antibody in the majority of individuals tested, regardless of Lyme disease history, limiting the usefulness of this antigen in Lyme disease serodiagnostic assays.

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