NYMC Faculty Publications

Histologic Observations of Periodontal Wound Healing After Treatment With PerioGlas in Nonhuman Primates

Author Type(s)

Faculty

Additional Author Affiliation

Touro College of Dental Medicine at NYMC

Journal Title

The International Journal of Periodontics & Restorative Dentistry

First Page

489

Last Page

499

Document Type

Article

Publication Date

10-1-1999

Department

Pharmacology

Abstract

The effect of PerioGlas (synthetic bone particulate) on wound healing of experimental palatal periodontal defects in monkeys was evaluated. Chronic periodontal defects were created on the palatal aspects of maxillary molars and premolars. Open-flap debridement was performed. Experimental sites received PerioGlas, while control sites received no further treatment. Histologic measurements were performed on new bone, new cementum, epithelial downgrowth, and recession. Results showed significantly more new cementum and less epithelial downgrowth in the sites that received PerioGlas (P < 0.05). The present results indicate that PerioGlas may enhance periodontal wound healing outcomes.

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