NYMC Faculty Publications

Regenerative Nanomedicine for Vision Restoration

Author Type(s)

Faculty

DOI

10.1016/j.mayocp.2013.05.025

Journal Title

Mayo Clinic Proceedings

First Page

1480

Last Page

1490

Document Type

Article

Publication Date

12-1-2013

Keywords

Blindness, Choroidal Neovascularization, Eye Diseases, Humans, Intraocular Pressure, Nanomedicine, Nanotechnology, Optic Nerve Diseases, Regenerative Medicine, Retinal Degeneration, Retinal Neovascularization, Vision Disorders, Vision, Ocular

Disciplines

Medicine and Health Sciences

Abstract

Herein, we discuss recent applications of nanotechnology to ophthalmology, including nanoparticles for drug, gene, and trophic factor delivery; regenerative medicine (in the areas of optogenetics and optic nerve regeneration); and diagnostics (eg, minimally invasive biometric monitoring). Specific applications for the management of choroidal neovascularization, retinal neovascularization, oxidative damage, optic nerve damage, and retinal degenerative disease are considered. Nanotechnology will play an important role in early- and late-stage interventions in the management of blinding diseases.

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