NYMC Faculty Publications

A Comprehensive Review of Benign Tumors in the Lung

Author Type(s)

Faculty

DOI

10.1097/MCP.0000000000001178

Journal Title

Current Opinion in Pulmonary Medicine

First Page

311

Last Page

320

Document Type

Article

Publication Date

7-1-2025

Department

Medicine

Keywords

benign lung tumor, lung mass, nodules, pathology, radiograph

Disciplines

Medicine and Health Sciences

Abstract

Purpose of reviewThe purpose of this review is to provide clinicians a comprehensive overview of the epidemiology, clinical symptoms, radiological features, pathological features, and management recommendations for the vast majority of benign lung tumors. Benign lung tumors are very rare with incidence ranging from 1 in 1000 to 1 in 1 million. Despite not being malignant, certain benign tumors carry significant morbidity and mortality along with diagnostic challenges.Recent findingsAdvancements in genomic sequencing have led to discovery of mutations in particular benign lung tumors. Improved genotyping have aided the diagnosis of certain tumors and the identification of lung lesions with malignant transformation potential. Genomic understanding has also led to targeted therapy for tumors with significant morbidity.SummaryDespite radiographic and pathologic advances in understanding benign lung tumors, the paucity of cases continues to impact management recommendations and early detection. Global collaborative initiatives in compiling and analyzing cases are essential for stronger evidence based management recommendations.

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