NYMC Faculty Publications
Thrombectomy Selection in the Large Core Era: Implications for Regional Transfers
Author Type(s)
Faculty
DOI
10.1007/s11910-025-01421-x
Journal Title
Current Neurology and Neuroscience Reports
Document Type
Article
Publication Date
12-1-2025
Department
Neurology
Keywords
Large core, Stroke, Tandem occlusion, Thrombectomy
Disciplines
Medicine and Health Sciences
Abstract
Purpose of Review: This review aims to evaluate recent advances in large core stroke management with a focus on diagnostic imaging protocols to select patients for endovascular therapy. Recent Findings: Recent randomized controlled trials have shown that thrombectomy can lead to favorable outcomes in patients with large infarcts, contradicting previous assumptions that thrombectomy was not indicated in such patients due to higher risks and very low benefits. Summary: Although mechanical thrombectomy remains the gold standard of medical treatment for large vessel occlusions with demonstrated salvageable brain tissue, analysis of the results of recent randomized trials in patients with large ischemic stroke should help us expand patient selection, optimize timing, and explore different management modalities to improve the outcomes of therapy in these patients.
Recommended Citation
Cirillo, L., Abdalkader, M., Klein, P., Yedavalli, V., Siegler, J., Kang, M., Shu, L., Al Mufti, F., Yaghi, S., Ranta, A., & Nguyen, T. (2025). Thrombectomy Selection in the Large Core Era: Implications for Regional Transfers. Current Neurology and Neuroscience Reports, 25 (1). https://doi.org/10.1007/s11910-025-01421-x
