Oral Leiomyomatous Hamartoma: Presentation of 3 Cases and Review of the Literature

Authors

Aaron E. Yancoskie, New York Medical College
Denise A. Trochesset, NYU College of Dentistry
David Merer, New York Medical College
John E. Fantasia, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell
Arthi M. Kumar, NYU College of Dentistry

Author Type(s)

Faculty

DOI

10.1016/j.oooo.2023.07.045

Journal Title

Oral Surgery Oral Medicine Oral Pathology and Oral Radiology

First Page

e1

Last Page

e7

Document Type

Article

Publication Date

1-1-2024

Department

Otolaryngology

Disciplines

Medicine and Health Sciences

Abstract

Oral leiomyomatous hamartoma (OLH) is a rare lesion, with only 40 cases reported in the literature. It typically presents early in life as a nodule on the anterior maxillary alveolar tissues or the tongue. Its growth potential is limited, with few cases reaching dimensions >2.0 cm, and its microscopic composition includes an intact surface mucosa with an underlying fibrovascular stroma possessing an unencapsulated proliferation of smooth muscle fascicles. Excision is considered the definitive treatment. Here we describe the clinical, microscopic, histochemical, and immunohistochemical features and management of 3 cases of OLH and review the literature. The findings we present here can assist in performing differential diagnosis, particularly in discriminating between OLH and similar yet non-hamartomatous processes and in selecting appropriate management.

Recommended Citation

Yancoskie, A., Trochesset, D., Merer, D., Fantasia, J., & Kumar, A. (2024). Oral Leiomyomatous Hamartoma: Presentation of 3 Cases and Review of the Literature. Oral Surgery Oral Medicine Oral Pathology and Oral Radiology, 137 (1), e1-e7. https://doi.org/10.1016/j.oooo.2023.07.045