NYMC Faculty Publications

Flowtriever System for Pulmonary Embolism a Review of Clinical Evidence

Author Type(s)

Faculty

DOI

10.1097/CRD.0000000000000605

Journal Title

Cardiology in Review

First Page

199

Last Page

201

Document Type

Article

Publication Date

5-1-2025

Department

Medicine

Keywords

acute pulmonary embolism, FlowTriever System, mechanical thrombectomy

Disciplines

Medicine and Health Sciences

Abstract

Pulmonary embolism (PE) is a significant cause of cardiovascular mortality, and its incidence has been increasing due to the growing aging population. Systemic or catheter-directed thrombolytic treatment for PE has an increased risk of bleeding that may offset the benefit in some patients. Mechanical thrombectomy devices such as the FlowTriever System are designed to resolve vascular occlusion and correct ventilation-perfusion mismatch without the need for thrombolytic drugs. This review covers the FlowTriever system, clinical data from the FlowTriever Pulmonary Embolectomy Clinical Study, FlowTriever for Acute Massive Pulmonary Embolism, and FlowTriever All-comer Registry for Patient Safety and Hemodynamics trials, and real-world experiences, demonstrating its safety and effectiveness in treating intermediate-risk and high-risk PE. Additionally, we explore off-label uses of the FlowTriever System for various large vessel thromboses.

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