NYMC Faculty Publications
Review of the Etiology, Diagnosis, and Management of Left Ventricular Thrombus
Author Type(s)
Resident/Fellow, Faculty
DOI
10.1097/CRD.0000000000000572
Journal Title
Cardiology in Review
First Page
46
Last Page
48
Document Type
Article
Publication Date
1-1-2025
Department
Medicine
Keywords
anticoagulation, direct oral anticoagulants, left ventricular thrombus, vitamin K antagonists
Disciplines
Medicine and Health Sciences
Abstract
The incidence of left ventricular (LV) thrombus following acute myocardial infarction has declined significantly due to recent advancements in reperfusion and antithrombotic therapies. The development of LV thrombus depends on Virchow's triad: endothelial injury following myocardial infarction, blood stasis from LV dysfunction, and hypercoagulability. Diagnostic modalities for LV thrombus include transthoracic echocardiography and late gadolinium enhancement cardiac magnetic resonance imaging. Anticoagulation with direct oral anticoagulants or vitamin K antagonists for 3 months following initial diagnosis of LV thrombus remains the treatment of choice for LV thrombus. However, further evidence is needed to demonstrate the noninferiority of direct oral anticoagulants compared with vitamin K antagonists for the prevention of thromboembolic events.
Recommended Citation
Feldman, J., Frishman, W., & Aronow, W. (2025). Review of the Etiology, Diagnosis, and Management of Left Ventricular Thrombus. Cardiology in Review, 33 (1), 46-48. https://doi.org/10.1097/CRD.0000000000000572
