NYMC Faculty Publications
Antimicrobial Resistance and Novel Alternative Approaches to Conventional Antibiotics
Author Type(s)
Faculty
DOI
10.3390/bacteria3030012
Journal Title
Bacteria
First Page
171
Last Page
182
Document Type
Article
Publication Date
9-1-2024
Department
Pathology, Microbiology and Immunology
Keywords
bacteriophage, cannabinoids, nanoparticles, ntibiotics, peptide, probiotics, resistance
Disciplines
Medicine and Health Sciences
Abstract
Antimicrobial resistance is a significant public health issue. The unprecedented spread of antimicrobial-resistant organisms has been identified by the World Health Organization as one of the leading healthcare threats. Projections for annual worldwide deaths attributed to antimicrobial resistance approach 10 million by 2050, with an associated economic burden of USD 100 trillion. This paper reviews the mechanisms known to contribute to antimicrobial resistance and provides insight into potential available alternatives to conventional antibiotics. Antimicrobial approaches addressed include dual antibiotic therapy, antimicrobial peptides, monoclonal antibodies, bacteriophages, probiotics, nanomaterials, and cannabinoids. Key pathogens in need of antimicrobials referred to as the ESKAPE pathogens are discussed.
Recommended Citation
Berger, I., & Loewy, Z. (2024). Antimicrobial Resistance and Novel Alternative Approaches to Conventional Antibiotics. Bacteria, 3 (3), 171-182. https://doi.org/10.3390/bacteria3030012
