NYMC Faculty Publications
Selective Cerebral Perfusion for Cerebral Protection: What We Do Know
Author Type(s)
Faculty
DOI
10.3978/j.issn.2225-319X.2013.03.02
Journal Title
Annals of Cardiothoracic Surgery
First Page
326
Last Page
330
Document Type
Article
Publication Date
5-1-2013
Department
Surgery
Disciplines
Medicine and Health Sciences
Abstract
Selective antegrade cerebral perfusion (SACP) for aortic arch surgery has evolved considerably since it was first reported. Various pressure rates have been investigated through animal models, as has the effect of warmer perfusate temperatures and hematocrit. Clinical research into pH management, the role of unilateral and bilateral perfusion, and core temperatures have further refined the procedure. We recommend the following protocol for SACP: perfusion pressure between 40-60 mmHg, flow rates between 6-10 mL/kg/min, and perfusate temperature of 20-28 °C; core cooling to 18-30 °C contingent on duration of arrest; alpha-stat pH management; hematocrit between 25-30%; near infrared spectroscopy to monitor cerebral perfusion; and bilateral perfusion when prolonged durations of SACP is anticipated.
Recommended Citation
Spielvogel, D., & Tang, G. H. (2013). Selective Cerebral Perfusion for Cerebral Protection: What We Do Know. Annals of Cardiothoracic Surgery, 2 (3), 326-330. https://doi.org/10.3978/j.issn.2225-319X.2013.03.02
