NYMC Faculty Publications

Incidence and Outcome of Procedural Distal Emboli Using the Penumbra Thrombectomy for Acute Stroke

Author Type(s)

Faculty

DOI

10.1136/neurintsurg-2011-010216

Journal Title

Journal of NeuroInterventional Surgery

First Page

135

Last Page

138

Document Type

Article

Publication Date

3-1-2013

Department

Neurology

Second Department

Neurosurgery

Keywords

Adult, Aged, Aged, 80 and over, Female, Humans, Incidence, Intracranial Embolism, Male, Middle Aged, Radiography, Retrospective Studies, Stroke, Thrombectomy, Treatment Outcome

Disciplines

Medicine and Health Sciences

Abstract

BACKGROUND: The Penumbra system is effective for recanalization of the primary arterial occlusion (PAO) in acute stroke. However, clinical outcomes are not as promising. The authors hypothesized that the formation of procedural distal emboli (PDE) during mechanical thrombectomy may lead to poorer patient outcomes.

DESIGN/METHODS: A retrospective review of patients with acute ischemic stroke treated with the Penumbra system was undertaken. Patients' outcome was evaluated by comparing discharge National Institute of Health stroke scale and modified Rankin score (mRS) of patients with and without PDE.

RESULTS: Out of 20 patients reviewed, recanalization of PAO was 100%. Six patients (30%) were confirmed to have PDE, of which two died (33.3%) and one (16.7%) had mRS of 2 or less. Of the 14 patients without PDE, three died (21.4%) and six (42.9%) had mRS of 2 or less. In the patient group who survived, mean National Institute of Health stroke scale decrease was only 2.3 in patients with PDE versus a decrease of 10.6 in patients without PDE.

CONCLUSIONS: In spite of PAO recanalization, distal emboli formed subsequent to Penumbra thrombectomy may contribute to poorer clinical outcome in acute stroke patients.

Link to Full Text

Share

COinS