NYMC Faculty Publications

Congenital Kaposiform Hemangioendothelioma With Kasabach-Merritt Phenomenon Successfully Treated With Low-Dose Radiation Therapy

Author Type(s)

Faculty

DOI

10.1111/pde.12090

Journal Title

Pediatric Dermatology

First Page

595

Last Page

598

Document Type

Article

Publication Date

1-1-2014

Department

Dermatology

Second Department

Pediatrics

Keywords

Diagnosis, Differential, Diagnostic Imaging, Hemangioendothelioma, Humans, Infant, Newborn, Kasabach-Merritt Syndrome, Male, Prenatal Diagnosis, Radiotherapy Dosage, Sarcoma, Kaposi

Disciplines

Medicine and Health Sciences

Abstract

Kaposiform hemangioendothelioma (KHE) associated with Kasabach-Merritt phenomenon is a life-threatening vasculopathy. The current mainstay treatment for KHEs is corticosteroids and chemotherapy, but these medications do not work for all patients and carry significant side effects. We report a neonate with a large congenital KHE who responded extremely well to low-dose radiation therapy.

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