NYMC Faculty Publications
Safe Oxygen Saturation Targeting and Monitoring in Preterm Infants: Can We Avoid Hypoxia and Hyperoxia?
Author Type(s)
Faculty
DOI
10.1111/apa.12692
Journal Title
Acta Paediatrica
First Page
1009
Last Page
1018
Document Type
Article
Publication Date
10-1-2014
Department
Pediatrics
Keywords
Humans, Hyperoxia, Hypoxia, Infant, Newborn, Infant, Premature, Intensive Care, Neonatal, Monitoring, Physiologic, Oxygen, Randomized Controlled Trials as Topic
Disciplines
Medicine and Health Sciences
Abstract
UNLABELLED: Oxygen is a neonatal health hazard that should be avoided in clinical practice. In this review, an international team of neonatologists and nurses assessed oxygen saturation (SpO2 ) targeting in preterm infants and evaluated the potential weaknesses of randomised clinical trials.
CONCLUSION: SpO2 of 85-89% can increase mortality and 91-95% can cause hyperoxia and ill effects. Neither of these ranges can be recommended, and wider intermediate targets, such as 87-94% or 88-94%, may be safer.
Recommended Citation
Sola, A., Golombek, S., Montes Bueno, M., Lemus-Varela, L., Zuluaga, C., Domínguez, F., Baquero, H., Young Sarmiento, A. E., Natta, D., Rodriguez Perez, J. M., Deulofeut, R., Quiroga, A., Flores, G., Morgues, M., Pérez, A., Van Overmeire, B., & van Bel, F. (2014). Safe Oxygen Saturation Targeting and Monitoring in Preterm Infants: Can We Avoid Hypoxia and Hyperoxia?. Acta Paediatrica, 103 (10), 1009-1018. https://doi.org/10.1111/apa.12692
