NYMC Faculty Publications
Intraventricular Thrombolysis After Endovascular Treatment of a Ruptured Arteriovenous Malformation
DOI
10.1136/neurintsurg-2016-012408.rep
Journal Title
Journal of Neurointerventional Surgery
First Page
e8
Document Type
Article
Publication Date
February 2017
Department
Neurosurgery
Abstract
Intraventricular haemorrhage (IVH) secondary to arteriovenous malformation (AVM) rupture carries significant morbidity and mortality. External ventricular drainage of IVH is frequently complicated by thrombus formation within the ventricular catheter and therefore often unsuccessful at treating hydrocephalus in this setting. Intraventricular administration of recombinant tissue-type plasminogen activator (rtPA) has proved successful in the treatment of spontaneous panventricular haemorrhage. However, usage of rtPA is contraindicated in the setting of a ruptured AVM or aneurysm in which the bleeding source has not been secured. There are only a few reports of intraventricular thrombolysis in the treatment of IVH from AVM rupture. We present the case of successful application of rtPA to treat IVH after endovascularly securing the haemorrhage site of the AVM. Intraventricular thrombolysis remains an option for the treatment of IVH in the setting of AVM rupture and should be considered on a case-by-case basis.
Recommended Citation
Wang, A., Ray, A., & Hu, Y. (2017). Intraventricular Thrombolysis After Endovascular Treatment of a Ruptured Arteriovenous Malformation. Journal of Neurointerventional Surgery, 9 (2), e8. https://doi.org/10.1136/neurintsurg-2016-012408.rep