NYMC Faculty Publications

Sojourn in Excessively High Oxygen Saturation Ranges in Individual, Very Low-Birthweight Neonates

Author Type(s)

Faculty

DOI

10.1111/apa.12827

Journal Title

Acta Paediatrica

First Page

51

Last Page

56

Document Type

Article

Publication Date

2-1-2015

Department

Pediatrics

Keywords

Continuous Positive Airway Pressure, High-Frequency Ventilation, Humans, Infant, Extremely Low Birth Weight, Infant, Extremely Premature, Infant, Newborn, Oximetry, Oxygen, Prospective Studies

Disciplines

Medicine and Health Sciences

Abstract

AIM: To investigate the variability in sojourn times at high oxygen saturations (SpO2 ) in individual patients and to examine whether there are subsets of patients or treatments that are associated with differing sojourn times at SpO2 ≥93%.

METHODS: Pulse oximetry data (Masimo) were studied in 71 premature babies receiving supplemental oxygen. Outcome measure was proportion of time per 12-h shift that individual babies spent in the range SpO2 ≥93%. We studied whether an inordinate proportion of time spent at SpO2 ≥93% was attributable to any subset of babies, mode of ventilation or nursing shifts, whether sojourn times were statistically independent shift-to-shift and whether an educational intervention reduced the amount of time spent at SpO2 ≥93%.

RESULTS: The proportion of time spent by the populations overall at SpO2 ≥93% was distributed equally among babies. However, high-frequency ventilation was associated with the least amount of time at SpO2 ≥93% compared with other modes of respiratory support (p < 0.0001), while nasal cannulae were associated with the highest proportion of time at SpO2 ≥93% (p < 0.001).

CONCLUSION: Measures to improve compliance with targeted SpO2 ranges should be applied universally although further improvement may be achieved by specifically targeting babies receiving supplemental oxygen via nasal cannula.

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