NYMC Faculty Publications
Assessment of Coronary Hemodynamics and Vascular Function
Author Type(s)
Faculty
DOI
10.1016/j.pcad.2014.11.006
Journal Title
Progress in Cardiovascular Diseases
First Page
423
Last Page
430
Document Type
Article
Publication Date
1-1-2015
Department
Physiology
Keywords
Animals, Biomarkers, Coronary Circulation, Coronary Disease, Coronary Vessels, Diagnostic Techniques, Cardiovascular, Hemodynamics, Humans, Predictive Value of Tests, Prognosis
Disciplines
Medicine and Health Sciences
Abstract
Coronary blood flow closely matches to metabolic demands of heart and myocardial oxygen consumption and is conditioned by function of coronary resistance vessels. The microvascular endothelium of coronary resistance vessels is exposed to a spatially and temporally regulated input from cardiomyocytes and the haemodynamic forces of the cardiac cycle. Functional measurements of coronary pressure and flow are important approaches that provide complementary information on the function of coronary vessel function that could not be assessed by the methods utilized for the anatomic characterization of coronary disease, such as coronary angiography. The goal of this paper is to review the methodologies for assessment of coronary vascular function and haemodynamics which are utilized in research and to discuss their potential applicability in the clinical settings.
Recommended Citation
Drenjancevic, I., Koller, A., Selthofer-Relatic, K., Grizelj, I., & Cavka, A. (2015). Assessment of Coronary Hemodynamics and Vascular Function. Progress in Cardiovascular Diseases, 57 (5), 423-430. https://doi.org/10.1016/j.pcad.2014.11.006
