NYMC Faculty Publications
Targeting the Neuropeptide Y System in Stress-Related Psychiatric Disorders
Author Type(s)
Faculty
DOI
10.1016/j.ynstr.2014.09.007
Journal Title
Neurobiology of Stress
First Page
33
Last Page
43
Document Type
Article
Publication Date
1-1-2015
Department
Cell Biology
Second Department
Neurology
Disciplines
Medicine and Health Sciences
Abstract
Repeated, extreme, or traumatic stressors can elicit pathological effects leading to many negative physical and psychological outcomes. Stressors can precipitate the onset of psychiatric diseases, or exacerbate pre-existing disorders including various anxiety and mood disorders. As stressors can negatively impact human psychiatric health, it is essential to identify neurochemicals that may confer protection from the negative sequelae of repeated or extreme stress exposure. Elucidating the neurobiological underpinnings of stress resilience will enhance our ability to promote resilience to, or recovery from, stress-related psychiatric disease. Herein, we will review the evidence for neuropeptide Y as an endogenous mediator of resilience and its potential relevance for the treatment of stress-related psychiatric diseases.
Recommended Citation
Enman, N. M., Sabban, E., McGonigle, P., & Van Bockstaele, E. J. (2015). Targeting the Neuropeptide Y System in Stress-Related Psychiatric Disorders. Neurobiology of Stress, 1, 33-43. https://doi.org/10.1016/j.ynstr.2014.09.007
