NYMC Faculty Publications

Probable Recurrence of Cardiac Sarcoidosis in a Transplanted Heart

Author Type(s)

Faculty, Resident/Fellow

DOI

10.1016/j.jhlto.2024.100146

Journal Title

JHLT Open

First Page

100146

Last Page

100146

Document Type

Case Report

Publication Date

11-2024

Department

Medicine

Second Department

Pathology, Microbiology and Immunology

Third Department

Surgery

Keywords

immunosuppression; cardiac sarcoidosis; graft dysfunction; orthotopic heart transplant; recurrent sarcoidosis

Disciplines

Medicine and Health Sciences

Abstract

Recurrence of cardiac sarcoidosis (CS) in post-transplant patients presents a rare but potentially life-threatening form of graft dysfunction and poses challenges due to varying clinical presentations, limited diagnostic modalities, and treatments based on anecdotal evidence. We discuss the case of a 46-year-old woman with CS, who developed cardiogenic shock necessitating orthotopic heart transplant. She subsequently developed likely recurrent CS in the transplanted heart. We discuss the rarity of this scenario as well as diagnostic modalities and management principles to consider.

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