NYMC Faculty Publications

Introducing a Special Collection of CME Articles About Long-Acting Injectable Antipsychotics

DOI

10.1017/S1092852925100722

Journal Title

Cns Spectrums

First Page

S43

Last Page

S44

Document Type

Article

Publication Date

12-24-2025

Department

Psychiatry and Behavioral Sciences

Disciplines

Medicine and Health Sciences

Abstract

Long-acting injectable (LAI) antipsychotics are not routinely offered and, thus, are underutilized despite their many advantages over oral formulations. In this special collection of articles, the reader will find overviews of the art and science of prescribing this important treatment option. Guidance is offered regarding incorporating LAIs in treatment planning, including inpatient, outpatient, and jail settings. Reviewed is the evidence surrounding the use of LAIs for patients in their first episode of schizophrenia, as well as switching from oral agents and other common issues that come up in day-to-day practice. Also provided is a comprehensive summary of each of the currently available formulations of LAIs, and some pragmatic reasons why one would be considered over another. In the end, the reader will come away with the notion that LAIs are not a “last resort” but an important and useful treatment modality that ought to be considered more often.

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