NYMC Faculty Publications

Cardiotoxicity of Breast Cancer Chemotherapy

DOI

10.1097/CRD.0000000000000589

Journal Title

Cardiology in Review

First Page

109

Last Page

111

Document Type

Article

Publication Date

3-1-2025

Department

Medicine

Keywords

anthracyclines, breast cancer, cardiotoxicity, chemotherapy, trastuzumab

Disciplines

Medicine and Health Sciences

Abstract

Breast cancer is one of the leading causes of malignancy affecting women in the United States. Although many effective treatments are available, most come with notable side effects that providers and patients must take into consideration. Various classes of chemotherapeutic agents, including anthracyclines and human epidermal growth factor receptor-2 antagonists, are known to be toxic to myocardial tissue. In this review article, we discuss what is reported in the literature regarding the cardiotoxicity of these agents as well as how to monitor and prevent cardiac injury and dysfunction.

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