Skull Metastasis With Orbital Invasion as a Primary Manifestation of Hepatocellular Carcinoma

Authors

• Samer Jumean, New York Medical College
• Shatha Elemian
• Hamid S. Shaaban, New York Medical CollegeFollow
• Gunwant Guron, New York Medical CollegeFollow

Author Type(s)

Resident/Fellow, Faculty

DOI

10.7759/cureus.55091

Journal Title

Cureus

First Page

55091

Last Page

55091

Document Type

Case Report

Publication Date

2-27-2024

Department

Medicine

Keywords

gastrointestinal oncology; bone metastasis; hepatocellular carcinoma (hcc); orbital invasion; skull metastasis; temporal skull lesion

Disciplines

Medicine and Health Sciences

Abstract

Hepatocellular carcinoma (HCC) is a common worldwide cancer with a poor prognosis despite treatment advancements. Patients typically exhibit signs and symptoms pertaining to the liver. Extrahepatic metastasis of HCC is documented to be as low as 5% of cases. Bone metastasis ranks third following lungs and regional lymph nodes. The typical locations for bone metastasis include the vertebral column, pelvis, femora, and ribs, with skull metastasis, being reported in less than 1.6% of cases. Herein, we describe a case of HCC presenting with skull metastases and orbital invasion as the initial manifestation.

Recommended Citation

Jumean, S., Elemian, S., Shaaban, H. S., & Guron, G. (2024). Skull Metastasis With Orbital Invasion as a Primary Manifestation of Hepatocellular Carcinoma. Cureus, 16 (2), 55091-55091. https://doi.org/10.7759/cureus.55091