NYMC Faculty Publications
Modeling Schizophrenia Pathogenesis Using Patient-Derived Induced Pluripotent Stem Cells (iPSCs)
DOI
10.1016/j.bbadis.2017.06.019
Journal Title
Biochimica Et Biophysica Acta-Molecular Basis of Disease
First Page
2382
Last Page
2387
Document Type
Article
Publication Date
9-1-2017
Department
Cell Biology and Anatomy
Abstract
Schizophrenia is a chronic disabling mental disorder that affects about 1% population world-wide, for which there is a desperate need to develop more effective treatments. In this minireview, we summarize the findings from recent studies using induced pluripotent stem cells to model the developmental pathogenesis of schizophrenia and discuss what we have learned from these studies. We also discuss what are the important next steps and key issues to be addressed to move the field forward.
Recommended Citation
Noh, H., Shao, Z., Coyle, J., & Chung, S. (2017). Modeling Schizophrenia Pathogenesis Using Patient-Derived Induced Pluripotent Stem Cells (iPSCs). Biochimica Et Biophysica Acta-Molecular Basis of Disease, 1863 (9), 2382-2387. https://doi.org/10.1016/j.bbadis.2017.06.019
