Results of the Covid-19 Mental Health International for the General Population (Comet-G) Study

Authors

Konstantinos N Fountoulakis
Grigorios Karakatsoulis
Seri AbrahamFollow
Kristina Adorjan
Helal Uddin AhmedFollow
Renato D AlarcónFollow
Kiyomi Arai
Sani Salihu Auwal
Michael Berk
Sarah Bjedov
Julio Bobes
Teresa Bobes-Bascaran
Julie Bourgin-Duchesnay
Cristina Ana Bredicean
Laurynas Bukelskis
Akaki Burkadze
Indira Indiana Cabrera Abud
Ruby Castilla-Puentes
Marcelo Cetkovich
Hector Colon-Rivera
Ricardo Corral
Carla Cortez-Vergara
Piirika Crepin
Domenico De Berardis
Sergio Zamora Delgado
David De Lucena
Avinash De Sousa
Ramona Di Stefano
Seetal Dodd
Livia Priyanka Elek
Anna Elissa
Berta Erdelyi-Hamza
Gamze Erzin
Martin J Etchevers
Peter Falkai
Adriana Farcas
Ilya Fedotov
Viktoriia Filatova
Nikolaos K Fountoulakis
Iryna Frankova
Francesco Franza
Pedro Frias
Tatiana Galako
Cristian J Garay
Leticia Garcia-Álvarez
Maria Paz García-Portilla
Xenia Gonda
Tomasz M Gondek
Daniela Morera González
Hilary Gould
Paolo Grandinetti
Arturo Grau
Violeta Groudeva
Michal Hagin
Takayuki Harada
M Tasdik Hasan
Nurul Azreen Hashim
Jan Hilbig
Sahadat Hossain
Rossitza Iakimova
Mona Ibrahim
Felicia Iftene
Yulia Ignatenko
Matias Irarrazaval
Zaliha Ismail
Jamila Ismayilova
Asaf Jacobs, New York Medical College
Miro Jakovljević
Nenad Jakšić
Afzal Javed
Helin Yilmaz Kafali
Sagar Karia
Olga Kazakova
Doaa Khalifa
Olena Khaustova
Steve Koh
Svetlana Kopishinskaia
Korneliia Kosenko
Sotirios A Koupidis
Illes Kovacs
Barbara Kulig
Alisha Lalljee
Justine Liewig
Abdul Majid
Evgeniia Malashonkova
Khamelia MalikFollow
Najma Iqbal MalikFollow
Gulay Mammadzada
Bilvesh Mandalia
Donatella Marazziti
Darko Marčinko
Stephanie Martinez
Eimantas Matiekus
Gabriela Mejia
Roha Saeed Memon
Xarah Elenne Meza Martínez
Dalia Mickevičiūtė
Roumen Milev
Muftau Mohammed
Alejandro Molina-López
Petr Morozov
Nuru Suleiman MuhammadFollow
Filip Mustač
Mika S Naor
Amira Nassieb
Alvydas Navickas
Tarek Okasha
Milena PandovaFollow
Anca-Livia PanfilFollow
Liliya PanteleevaFollow
Ion Papava
Mikaella E Patsali
Alexey Pavlichenko
Bojana Pejuskovic
Mariana Pinto Da Costa
Mikhail Popkov
Dina Popovic
Nor Jannah Nasution Raduan
Francisca Vargas Ramírez
Elmars Rancans
Salmi Razali
Federico Rebok
Anna Rewekant
Elena Ninoska Reyes Flores
María Teresa Rivera-Encinas
Pilar Saiz
Manuel Sánchez de Carmona
David Saucedo Martínez
Jo Anne Saw
Görkem Saygili
Patricia Schneidereit
Bhumika Shah
Tomohiro Shirasaka
Ketevan Silagadze
Satti Sitanggang
Oleg Skugarevsky
Anna Spikina
Sridevi Sira Mahalingappa
Maria Stoyanova
Anna Szczegielniak
Simona Claudia Tamasan
Giuseppe Tavormina
Maurilio Giuseppe Maria Tavormina
Pavlos N Theodorakis
Mauricio Tohen
Eva Maria Tsapakis
Dina Tukhvatullina
Irfan Ullah
Ratnaraj Vaidya
Johann M Vega-Dienstmaier
Jelena Vrublevska
Olivera Vukovic
Olga Vysotska
Natalia Widiasih
Anna Yashikhina
Panagiotis E Prezerakos
Daria Smirnova

Author Type(s)

Resident/Fellow

Document Type

Article

Publication Date

1-1-2022

DOI

10.1016/j.euroneuro.2021.10.004

Journal Title

European Neuropsychopharmacology

Department

Psychiatry and Behavioral Sciences

Abstract

INTRODUCTION: There are few published empirical data on the effects of COVID-19 on mental health, and until now, there is no large international study.

MATERIAL AND METHODS: During the COVID-19 pandemic, an online questionnaire gathered data from 55,589 participants from 40 countries (64.85% females aged 35.80 ± 13.61; 34.05% males aged 34.90±13.29 and 1.10% other aged 31.64±13.15). Distress and probable depression were identified with the use of a previously developed cut-off and algorithm respectively.

STATISTICAL ANALYSIS: Descriptive statistics were calculated. Chi-square tests, multiple forward stepwise linear regression analyses and Factorial Analysis of Variance (ANOVA) tested relations among variables.

RESULTS: Probable depression was detected in 17.80% and distress in 16.71%. A significant percentage reported a deterioration in mental state, family dynamics and everyday lifestyle. Persons with a history of mental disorders had higher rates of current depression (31.82% vs. 13.07%). At least half of participants were accepting (at least to a moderate degree) a non-bizarre conspiracy. The highest Relative Risk (RR) to develop depression was associated with history of Bipolar disorder and self-harm/attempts (RR = 5.88). Suicidality was not increased in persons without a history of any mental disorder. Based on these results a model was developed.

CONCLUSIONS: The final model revealed multiple vulnerabilities and an interplay leading from simple anxiety to probable depression and suicidality through distress. This could be of practical utility since many of these factors are modifiable. Future research and interventions should specifically focus on them.

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