Genetic Determinants of the Re-Emergence of Arboviral Diseases
Author Type(s)
Student
Document Type
Article
Publication Date
2-12-2019
DOI
10.3390/v11020150
Journal Title
Viruses
Keywords
Animals, Arbovirus Infections, Arboviruses, Chikungunya Fever, Communicable Diseases, Emerging, Dengue, Evolution, Molecular, Genetic Fitness, Host Microbial Interactions, Humans, Mice, Mosquito Vectors, Public Health, Yellow Fever
Disciplines
Infectious Disease | Medicine and Health Sciences
Abstract
Mosquito-borne diseases constitute a large portion of infectious diseases, causing more than 700,000 deaths annually. Mosquito-transmitted viruses, such as yellow fever, dengue, West Nile, chikungunya, and Zika viruses, have re-emerged recently and remain a public health threat worldwide. Global climate change, rapid urbanization, burgeoning international travel, expansion of mosquito populations, vector competence, and host and viral genetics may all together contribute to the re-emergence of arboviruses. In this brief review, we summarize the host and viral genetic determinants that may enhance infectivity in the host, viral fitness in mosquitoes and viral transmission by mosquitoes.
Recommended Citation
Ketkar, H., Herman, D., & Wang, P. (2019). Genetic Determinants of the Re-Emergence of Arboviral Diseases. Viruses, 11 (2), 10.3390/v11020150. https://doi.org/10.3390/v11020150
