Comparative Analysis of Low-Dose Oral Minoxidil With Spironolactone versus Finasteride or Dutasteride in Female Androgenetic Alopecia Management

Author Type(s)

Student

Document Type

Article

Publication Date

9-14-2024

DOI

10.1007/s00403-024-03361-x

Journal Title

Archives of Dermatological Research

Abstract

LDOM has enhanced treatment options for female AGA, yet its combined efficacy with therapies such as spironolactone, finasteride, or dutasteride remains inadequately explored. This study aims to compare the efficacy and safety of LDOM in combination with spironolactone versus LDOM with finasteride or dutasteride in women with AGA. Our analysis revealed that both combination therapies produced similar improvements in hair growth and had comparable safety profiles. Although the LDOM with finasteride/dutasteride group showed a greater average increase in hair width and density, these differences were not statistically significant. These results endorse the use of LDOM in combination with either spironolactone or finasteride/dutasteride for female AGA, and underscore the necessity for further research to validate these findings and assess long-term treatment outcomes.

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