Nortriptyline-induced oral ulceration: A case report.

Author ORCID Identifier

https://orcid.org/0000-0001-6258-8653

https://orcid.org/0000-0003-3339-9671

Document Type

Article

Publication Date

11-1-2018

Publication Title

The Mental Health Clinician

DOI

10.9740/mhc.2018.11.309

Abstract

Drug-induced oral ulcers are lesions of the oral mucosa accompanied by painful symptoms, such as burning mouth, metallic taste, dysgeusia, or ageusia. This report demonstrates the first documented case of drug-induced oral ulcers with the tricyclic antidepressant nortriptyline. In this case, a 49-year-old female initiated treatment for refractory neuropathy with nortriptyline. Within 2 weeks of therapy, painful, oral, bubble-like ulcers developed. Complete symptom resolution occurred approximately 1 month after discontinuation of nortriptyline. Clinicians should be cognizant of nortriptyline's ability to potentially induce oral ulcers; however, the exact mechanism for this adverse event is unknown.

Creative Commons License

Creative Commons Attribution-Noncommercial 3.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial 3.0 License

Share

COinS