NYMC Faculty Publications
The Use of 1-Fluoro-2,4-Dinitrobenzene as an Affinity Label for the Antigen Receptor of Delayed Hypersensitivity
Journal Title
Immunology
First Page
665
Last Page
673
Document Type
Article
Publication Date
October 1976
Department
Pathology, Microbiology and Immunology
Abstract
The passive transfer of delayed contact sensitivity to dinitrophenyl can be specifically inhibited by brief treatment of lymph node cells (LNC) from sensitized guinea-pigs with 1-fluoro-2,4-dinitrobenzene (DNFB). Analysis of KC1 extracts of LNC previously treated with (3H)DNFB, using polyacrylamide gel electrophoresis, revealed a peak of radioactivity present in both sensitive and normal cell extracts as well as a peak found only in sensitive cell extracts. Cell-free extracts appeared capable of transmitting delayed-onset skin reactivity to non-sensitized recipients.
Recommended Citation
Godfrey, H. P. (1976). The Use of 1-Fluoro-2,4-Dinitrobenzene as an Affinity Label for the Antigen Receptor of Delayed Hypersensitivity. Immunology, 31 (4), 665-673. Retrieved from https://touroscholar.touro.edu/nymc_fac_pubs/1705
