NYMC Faculty Publications

Curative Resection of a Duodenal Gastrointestinal Stromal Tumor in the Setting of von Willebrand's Disease

DOI

10.1093/jscr/rjaa081

Journal Title

Journal of Surgical Case Reports

First Page

081

Last Page

081

Document Type

Case Report

Publication Date

4-24-2020

Department

Surgery

Abstract

Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the alimentary tract and usually presents with gastrointestinal hemorrhage. The diagnosis of GIST is typically made with upper endoscopy after excluding other causes of bleeding. The surgical management of GIST can be challenging depending upon the location of the tumor. We present a unique case of duodenal GIST in the setting von Willebrand's disease diagnosed after emergent laparotomy for massive gastrointestinal hemorrhage. Key strategies in curing our patient were treating the underlying bleeding disorder, collaborating with radiology and gastroenterology teams, and early exploratory laparotomy for refractory hemorrhage. This case demonstrates the challenges of diagnosing and managing GIST in patients with underlying coagulopathies.

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