NYMC Faculty Publications
Gastrointestinal Alpha Heavy Chain Disease With Persistent Campylobacter Jejuni Colonization and Refractory Giardiasis
Author Type(s)
Resident/Fellow, Faculty
DOI
10.14309/crj.0000000000001467
Journal Title
ACG Case Reports Journal
First Page
e01467
Document Type
Article
Publication Date
8-1-2024
Department
Medicine
Second Department
Pathology, Microbiology and Immunology
Abstract
Alpha heavy chain disease (αHCD) is a rare variant of the mucosa-associated lymphoid tissue lymphoma characterized by expression of a monotypic truncated immunoglobulin α heavy chain. αHCD frequently involves the gastrointestinal (GI) tract, and its pathogenesis has been linked to clonal B-cell expansion from chronic immune stimulation by infectious agents. We report a rare case of GI αHCD with 5 concomitant pathogens identified on a GI multiplex real-time polymerase chain reaction panel, featured by persistent Campylobacter jejuni colonization and refractory giardiasis.
Recommended Citation
Tang, W., Lin, Z., Sharma, P., Heering, G., Dworkin, B., Steinberg, A., Shakil, F., & Schorr-Lesnick, B. (2024). Gastrointestinal Alpha Heavy Chain Disease With Persistent Campylobacter Jejuni Colonization and Refractory Giardiasis. ACG Case Reports Journal, 11 (8), e01467. https://doi.org/10.14309/crj.0000000000001467