Gastrointestinal Alpha Heavy Chain Disease With Persistent Campylobacter Jejuni Colonization and Refractory Giardiasis

Authors

• Wei Tang, New York Medical College
• Zilan Lin, New York Medical College
• Pritika Sharma, New York Medical College
• Gabriel Heering, New York Medical College
• Brad Dworkin, New York Medical CollegeFollow
• Amir Steinberg, New York Medical CollegeFollow
• Fouzia Shakil, New York Medical CollegeFollow
• Beth Schorr-Lesnick, New York Medical CollegeFollow

Author Type(s)

Faculty, Resident/Fellow

DOI

10.14309/crj.0000000000001467

Journal Title

ACG Case Reports Journal

First Page

01467

Last Page

01467

Document Type

Case Report

Publication Date

8-22-2024

Department

Medicine

Second Department

Pathology, Microbiology and Immunology

Disciplines

Medicine and Health Sciences

Abstract

Alpha heavy chain disease (αHCD) is a rare variant of the mucosa-associated lymphoid tissue lymphoma characterized by expression of a monotypic truncated immunoglobulin α heavy chain. αHCD frequently involves the gastrointestinal (GI) tract, and its pathogenesis has been linked to clonal B-cell expansion from chronic immune stimulation by infectious agents. We report a rare case of GI αHCD with 5 concomitant pathogens identified on a GI multiplex real-time polymerase chain reaction panel, featured by persistent Campylobacter jejuni colonization and refractory giardiasis.

Recommended Citation

Tang, W., Lin, Z., Sharma, P., Heering, G., Dworkin, B., Steinberg, A., Shakil, F., & Schorr-Lesnick, B. (2024). Gastrointestinal Alpha Heavy Chain Disease With Persistent Campylobacter Jejuni Colonization and Refractory Giardiasis. ACG Case Reports Journal, 11 (8), 01467-01467. https://doi.org/10.14309/crj.0000000000001467