NYMC Faculty Publications
Role of Magnesium in Cardiovascular Diseases
Author Type(s)
Faculty
DOI
10.1097/CRD.0000000000000003
Journal Title
Cardiology in Review
First Page
182
Last Page
192
Document Type
Article
Publication Date
1-1-2014
Department
Pharmacology
Second Department
Medicine
Keywords
Animals, Anti-Arrhythmia Agents, Arrhythmias, Cardiac, Cardiovascular Agents, Cardiovascular Diseases, Disease Models, Animal, Endothelium, Vascular, Homeostasis, Humans, Magnesium, Magnesium Deficiency, Myocardial Ischemia, Myocytes, Smooth Muscle
Disciplines
Medicine and Health Sciences
Abstract
Magnesium, the fourth most abundant cation in the human body, is involved in several essential physiological, biochemical, and cellular processes regulating cardiovascular function. It plays a critical role in modulating vascular smooth muscle tone, endothelial cell function, and myocardial excitability and is thus central to the pathogenesis of several cardiovascular disorders such as hypertension, atherosclerosis, coronary artery disease, congestive heart failure, and cardiac arrhythmias. This review discusses the vasodilatory, anti-inflammatory, anti-ischemic, and antiarrhythmic properties of magnesium and its current role in the prevention and treatment of cardiovascular disorders.
Recommended Citation
Kolte, D., Vijayaraghavan, K., Khera, S., Sica, D. A., & Frishman, W. (2014). Role of Magnesium in Cardiovascular Diseases. Cardiology in Review, 22 (4), 182-192. https://doi.org/10.1097/CRD.0000000000000003
