A Drug-Like Molecule Engages Nuclear Hormone Receptor DAF-12/FXR To Regulate Mitophagy and Extend Lifespan

Authors

Manish Chamoli
Anand Rane
Anna Foulger
Shankar J. Chinta, Touro University CaliforniaFollow
Azar Asadi Shahmirzadi
Caroline Kumsta
Dhanya K. Nambiar
David Hall
Angelina Holcom
Suzanne AngeliFollow
Minna Schmidt
Sharon Pitteri
Malene Hansen
Gordon J. Lithgow
Julie K. Andersen

Roles

Author

Document Type

Article

Publication Date

1-1-2023

Publication Title

Nature Aging

DOI

10.1038/s43587-023-00524-9

Recommended Citation

Chamoli, M., Rane, A., Foulger, A., Chinta, S. J., Shahmirzadi, A. A., Kumsta, C., Nambiar, D. K., Hall, D., Holcom, A., Angeli, S., Schmidt, M., Pitteri, S., Hansen, M., Lithgow, G. J., & Andersen, J. K. (2023). A Drug-Like Molecule Engages Nuclear Hormone Receptor DAF-12/FXR To Regulate Mitophagy and Extend Lifespan. Nature Aging, 3, 1529–1543. https://doi.org/10.1038/s43587-023-00524-9